KMID : 0363220180560020114
|
|
Korean Journal of Dermatology 2018 Volume.56 No. 2 p.114 ~ p.120
|
|
Clinical Features and Total Immunoglobulin E Serum Levels in Patients with Nummular Eczema
|
|
Kim Hong-Lim
Jung Hye-Jung Park Mi-Youn Ahn Ji-Young
|
|
Abstract
|
|
|
Background: Nummular eczema (NE) is predominantly a disease of adulthood that presents as coin-shaped plaques from coalescing papulovesicles. Clinical manifestations vary from minimal to severe. The pathogenesis of NE is still unknown.
Objective: In this retrospective study, we sought to investigate the epidemiology, clinical manifestation, and abnormal laboratory findings in patients with NE.
Methods: We identified patients with NE who had visited the department of dermatology in National Medical Center between 2012 and 2015. The clinical charts and laboratory tests from each patients¡¯ medical record were reviewed.
Results: Overall, 244 patients with a median age was 52 years were identified; two-thirds were men. The onset of lesions predominantly occurred in patients¡¯ fifties and sixties. Predominant sites were the lower limbs, followed by the trunk and upper limbs. Twenty-six patients had a history of atopic diseases and 50 patients had elevated serum Ig E levels. The multiple allergosorbent test (MAST) was performed in 21 patients with an elevated serum Ig E level using an immunoblot assay. Dermatophagoides farinae, D. pteronyssinus, and house dust were common allergens found in MAST (76.2%, 76.2%, and 47.6%, respectively).
Conclusion: In this study, we found that NE developed mainly in elderly patients and that lesions were distributed on the lower limbs. In addition, 44% of the patients had an elevated serum Ig E level and 76.2% of patients had a positive response to house dust mites on the MAST. We hope that these data will help to understand the characteristic of nummular eczema.
|
|
KEYWORD
|
|
Nummular eczema, Discoid eczema, Serum Ig E level, Multiple allergosorbent test, MAST
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|